Cytokeratin 13 抗体
Quick Overview for Cytokeratin 13 抗体 (ABIN6937655)
抗原
See all Cytokeratin 13 (KRT13) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Cytokeratin 13 (KRT13) is the major acidic keratin, which together with KRT4, its basic partner, is expressed in the suprabasal layers of non-cornified stratified epithelia including tongue mucosa, esophagus, anal canal epithelium, tracheal epithelium, uterine cervix, and urothelium. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder, which predominantly affects non-cornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. KRT13 has been used as a marker for non-keratinized squamous epithelium. It is also expressed in various squamous metaplasia, but it is down regulated in squamous dysplasia and squamous carcinoma.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human KRT13 protein
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亚型
- IgG
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anti-Keratin 13 (KRT13) (N-Term) antibody
KRT13 适用: 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 13 (KRT13) (AA 104-403) antibodyKRT13 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 13 (KRT13) antibodyKRT13 适用: 人 WB, IHC (p), IF, ICC, IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 13 (KRT13) (C-Term) antibodyKRT13 适用: 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 13 (KRT13) (AA 104-458) antibodyKRT13 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7D7B3 unconjugated
anti-Keratin 13 (KRT13) (AA 269-458) antibodyKRT13 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 13 (KRT13) (AA 143-295) antibodyKRT13 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3G4 unconjugated
anti-Keratin 13 (KRT13) antibodyKRT13 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 5A3 unconjugated
anti-Keratin 13 (KRT13) antibodyKRT13 适用: 人 IHC, IF, StM 宿主: 小鼠 Monoclonal KRT13-2213 unconjugated
anti-Keratin 13 (KRT13) (AA 258-357) antibodyKRT13 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4F5 unconjugated
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应用备注
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Known_Application: Immunofluorescence (1-2 μg/mL), Flow Cytometry (1-2 μg per million cells), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or A431 cells. Skin or squamous cell carcinoma.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))
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别名
- KRT13
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背景
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CK13, Cytokeratin-13, Keratin Type I Cytoskeletal 13, Keratin-13, KRT13, Type I Cytoskeletal 13, WSN2,Cytokeratin 13 (Non-Keratinized Squamous Epithelial Marker)
Cellular localisation: Cytoplasmic -
分子量
- 52kDa
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基因ID
- 3860, 654550
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UniProt
- P13646
抗原
-
