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Cytokeratin 1 抗体 (C-Term)

KRT1 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal LHK1 unconjugated
产品编号 ABIN6937639
发货至: 中国
  • 抗原 See all Cytokeratin 1 (KRT1) 抗体
    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
    抗原表位
    • 20
    • 16
    • 16
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 87
    • 54
    • 41
    • 24
    • 16
    • 13
    • 8
    • 8
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    宿主
    • 70
    • 36
    • 1
    小鼠
    克隆类型
    • 63
    • 44
    单克隆
    标记
    • 45
    • 12
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cytokeratin 1 antibody is un-conjugated
    应用范围
    • 78
    • 51
    • 29
    • 28
    • 27
    • 26
    • 22
    • 17
    • 17
    • 14
    • 13
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Cytokeratin 1 is a hetero-tetramer of two type I as well as two type II keratins, keratin-10 (KRT10). Keratin 1 is differentiation specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epithelia. Mutations in keratin 1 cause epidermolytic hyperkeratosis.
    交叉反应 (详细)
    Human. Rat.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    A 13-amino acid peptide (VRFVSTSYSGVTR) from the C-terminus of human KRT1 protein
    克隆位点
    LHK1
    亚型
    IgG2a kappa
    Top Product
    Discover our top product KRT1 Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Skin or Cervix.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
    别名
    KRT1 (KRT1 产品)
    背景
    67 kDa Cytokeratin, CK1, Cytokeratin-1, EHK1, Epidermolytic hyperkeratosis 1, EPPK, K1, Keratin Type II Cytoskeletal 1, Keratin-1, KRT1, KRT1A, NEPPK, Type II cytoskeletal 1, Type-II keratin Kb1,Cytokeratin 1 (Suprabasal Keratinocyte Marker)
    Cellular localisation: Cytoplasmic
    分子量
    67kDa
    基因ID
    38748, 80828
    UniProt
    P04264
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