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Cytokeratin 1 抗体 (C-Term)

This anti-Cytokeratin 1 antibody is a 小鼠 单克隆 antibody detecting Cytokeratin 1 in IHC (f). Suitable for 人.
产品编号 ABIN6937639
发货至: 中国

Quick Overview for Cytokeratin 1 抗体 (C-Term) (ABIN6937639)

抗原

See all Cytokeratin 1 (KRT1) 抗体
Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

适用

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宿主

  • 76
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  • 1
小鼠

克隆类型

  • 69
  • 55
单克隆

标记

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This Cytokeratin 1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

LHK1
  • 抗原表位

    • 20
    • 16
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    • 5
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    • 2
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    • 2
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Cytokeratin 1 is a hetero-tetramer of two type I as well as two type II keratins, keratin-10 (KRT10). Keratin 1 is differentiation specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epithelia. Mutations in keratin 1 cause epidermolytic hyperkeratosis.

    交叉反应 (详细)

    Human. Rat.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    A 13-amino acid peptide (VRFVSTSYSGVTR) from the C-terminus of human KRT1 protein

    亚型

    IgG2a kappa
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Skin or Cervix.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

    别名

    KRT1

    背景

    67 kDa Cytokeratin, CK1, Cytokeratin-1, EHK1, Epidermolytic hyperkeratosis 1, EPPK, K1, Keratin Type II Cytoskeletal 1, Keratin-1, KRT1, KRT1A, NEPPK, Type II cytoskeletal 1, Type-II keratin Kb1,Cytokeratin 1 (Suprabasal Keratinocyte Marker)
    Cellular localisation: Cytoplasmic

    分子量

    67kDa

    基因ID

    38748, 80828

    UniProt

    P04264
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