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Recombinant IL3RA 抗体 (AA 26-171)

This anti-IL3RA antibody is a 兔 单克隆 antibody detecting IL3RA in ELISA, ISt, Coat 和 IHC (f). Suitable for 人.
产品编号 ABIN6937562
发货至: 中国

Quick Overview for Recombinant IL3RA 抗体 (AA 26-171) (ABIN6937562)

抗原

See all IL3RA 抗体
IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This IL3RA antibody is un-conjugated

应用范围

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ELISA, Immunostaining (ISt), Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

IL3RA-2947R
  • 抗原表位

    • 37
    • 16
    • 4
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    • 2
    • 2
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    AA 26-171

    特异性

    CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant fragment of human IL3RA protein (around aa 26-171) (exact sequence is proprietary)

    亚型

    IgG
  • 应用备注

    Known_Application: ELISA (For coating, order antibody without BSA),Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: THP-1, RPMI-8226 or HDLM-2 cells. Tonsil, Lymph Node or Stomach.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

    别名

    IL3RA

    背景

    CD123, hIL3Ra, IL-3R-alpha, IL-3RA, IL3RAX, IL3RAY, IL3RX, IL3RY, Interleukin-3 Receptor, alpha, Interleukin3 receptor, Interleukin3 receptor, Y-chromosomal,IL3RA / CD123 (Acute Myeloid Leukemia Marker)
    Cellular localisation: Cell Surface and Cytoplasmic

    分子量

    ~70kDa

    基因ID

    3563, 632790

    UniProt

    P26951

    途径

    JAK/STAT Signaling
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