IL-10RA 抗体
Quick Overview for IL-10RA 抗体 (ABIN6937553)
抗原
See all IL-10RA (IL10RA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.
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无交叉反应
- 人
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纯化方法
- Purified by Protein A/G
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免疫原
- Purified recombinant extracellular region of Mouse IL10RA
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亚型
- IgG1 kappa
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应用备注
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Positive Control: MPBMC's. Spleen, Thymus, Lymph Node, Placenta, Lung or Liver.
Known Application: Neutralization Studies (Order Ab without Azide),Flow Cytometry (0.5-1 μg/million cells in 0.1ml), Immunofluorescence (0.5-1 μg/mL)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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缓冲液
- 10 mM PBS without BSA and without Azide.
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储存液
- Azide free
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.
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有效期
- 24 months
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- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
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别名
- IL-10R1
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分子量
- 90-110kDa
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基因ID
- 16154
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UniProt
- Q61727
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途径
- Growth Factor Binding
抗原
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