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IGHM 抗体

IGHM 适用: 人 IHC, WB, IHC (f) 宿主: 小鼠 Monoclonal IM260 unconjugated
产品编号 ABIN6937515
发货至: 中国
  • 抗原 See all IGHM products
    IGHM (Immunoglobulin Heavy Constant mu (IGHM))
    适用
    • 25
    • 1
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    宿主
    • 13
    • 12
    小鼠
    克隆类型
    • 16
    • 9
    单克隆
    标记
    • 21
    • 1
    • 1
    • 1
    • 1
    This IGHM antibody is un-conjugated
    应用范围
    • 12
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    • 11
    • 8
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    • 7
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    Immunohistochemistry (IHC), Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant heavy chain of human IgM
    克隆位点
    IM260
    亚型
    IgG1 kappa
  • 应用备注

    Known_Application: Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: 293T, Raji or hPBL cells. Human tonsil or spleen (IHC).

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    IGHM (Immunoglobulin Heavy Constant mu (IGHM))
    别名
    IGHM (IGHM 产品)
    别名
    AI326478 antibody, Igh-6 antibody, Igh-M antibody, Igh6 antibody, Igm antibody, muH antibody, ighm1 antibody, wu:fj14a08 antibody, zgc:101769 antibody, AGM1 antibody, MU antibody, VH antibody, immunoglobulin heavy constant mu antibody, Ighm antibody, ighm antibody, IGHM antibody
    背景
    AGM1, IGHM, Constant Region of Heavy Chain of IgM, Ig Mu Chain C Region,IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker)
    Cellular localisation: Cytoplasm, Cell Surface and Secreted
    分子量
    50-75kDa
    基因ID
    3507, 510635
    UniProt
    P01871, P20769
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