IGHM 抗体
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- 抗原 See all IGHM products
- IGHM (Immunoglobulin Heavy Constant mu (IGHM))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IGHM antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. IgM antibody is prominent in early immune responses to most antigens. Aberrant levels are associated with immune deficiency states, hereditary deficiencies, myeloma, Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Heavy chain of human IgM
- 克隆位点
- ICO-30
- 亚型
- IgG1 kappa
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anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 310-452) antibody
IGHM 适用: 人 IHC, WB, FACS, ELISA 宿主: 小鼠 Monoclonal 8B9D3 unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, WB 宿主: 兔 Monoclonal unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM, ISt 宿主: 兔 Monoclonal IGHM-3776R unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, WB, StM, FACS, IF 宿主: 小鼠 Monoclonal IM373 unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 45-178) antibodyIGHM 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 1-489) antibodyIGHM 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM 宿主: 兔 Monoclonal IGHM-3135R unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rIM373 unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM, FACS, IF, ELISA, Coat 宿主: 小鼠 Monoclonal rIGHM-1623 unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 103-131) antibodyIGHM 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: 293T, Raji or hPBL cells. Tonsil or Spleen.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- IGHM (Immunoglobulin Heavy Constant mu (IGHM))
- 别名
- IGHM (IGHM 产品)
- 背景
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AGM1, IGHM, Constant Region of Heavy Chain of IgM, Ig Mu Chain C Region,IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker)
Cellular localisation: Cytoplasm, Cell Surface and Secreted - 分子量
- 50-75kDa
- 基因ID
- 3507, 510635
- UniProt
- P01871, P20769
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