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IFNA1 抗体

This anti-IFNA1 antibody is a 小鼠 单克隆 antibody detecting IFNA1 in WB, FACS, IF 和 IHC (fro). Suitable for 人.
产品编号 ABIN6937475
发货至: 中国

Quick Overview for IFNA1 抗体 (ABIN6937475)

抗原

See all IFNA1 抗体
IFNA1 (Interferon, alpha 1 (IFNA1))

适用

  • 63
  • 12
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宿主

  • 48
  • 19
  • 2
小鼠

克隆类型

  • 50
  • 19
单克隆

标记

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  • 2
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  • 1
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This IFNA1 antibody is un-conjugated

应用范围

  • 33
  • 26
  • 14
  • 12
  • 9
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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

Feb-48
  • 特异性

    This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Purified recombinant human IFN-alpha1

    亚型

    IgG1 kappa
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Immunohistochemistry (frozen), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: Stimulated human peripheral blood mononuclear cells.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    IFNA1 (Interferon, alpha 1 (IFNA1))

    别名

    IFNA1

    背景

    IFN alpha, IFN alpha 1/13, IFN alpha 1b, Interferon alpha 13 (IFNA13), Interferon alpha leukocyte (IFL), Interferon alpha-1/13 (IFN-alpha-1/13), Interferon alpha-D (IFN alphaD), Interferon alpha1 (IFNA1), LeIF D,Interferon alpha-1 (IFNA1)
    Cellular localisation: Cytoplasmic & Extracellular (Secreted)

    分子量

    16-27kDa

    基因ID

    3439, 37026, 533471

    UniProt

    P01562

    途径

    JAK/STAT Signaling, Hepatitis C
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