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HNF1A 抗体 (AA 214-339)

This anti-HNF1A antibody is a 小鼠 单克隆 antibody detecting HNF1A in ELISA, Coat 和 IHC (f). Suitable for 人.
产品编号 ABIN6937423
发货至: 中国

Quick Overview for HNF1A 抗体 (AA 214-339) (ABIN6937423)

抗原

See all HNF1A 抗体
HNF1A (HNF1 Homeobox A (HNF1A))

适用

  • 75
  • 50
  • 30
  • 7
  • 7
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  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
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宿主

  • 60
  • 17
  • 1
小鼠

克隆类型

  • 61
  • 17
单克隆

标记

  • 38
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
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  • 2
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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This HNF1A antibody is un-conjugated

应用范围

  • 53
  • 21
  • 15
  • 15
  • 14
  • 12
  • 7
  • 6
  • 5
  • 1
  • 1
  • 1
  • 1
ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

HNF1A-2087
  • 抗原表位

    • 16
    • 11
    • 10
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 214-339

    特异性

    HNF1A belongs to the homeobox protein family and is an essential transcription factor for many hepatic genes involved in detoxification, homeostasis and metabolisms of glucose, lipid, steroid and amino acid. In addition, HNF1A is an important component of the transcriptional networks governing embryonic pancreas development and differentiation. as well as maintaining the growth and function of islet cells in adult. HNF1A (Hepatocyte nuclear factor 1 alpha) is a transcription factor that is known to regulate pancreatic differentiation and maintain homeostasis of endocrine pancreas. Recently, genome-wide association studies have implicatedHNF1Aas a susceptibility gene for pancreatic cancer.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant fragment (around aa 214-339) of human HNF1A protein (exact sequence is proprietary)

    亚型

    IgG1 kappa
  • 应用备注

    Known_Application: ELISA (For coating, order antibody without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Jurkat cells. Small Intestine or Pancreas.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    HNF1A (HNF1 Homeobox A (HNF1A))

    别名

    HNF1A

    背景

    Albumin proximal factor, Hepatic nuclear factor 1 alpha, Hepatic transcription factor 1 alpha, HNF-1A, Interferon production regulator factor, LFB1, LFB1 hepatic nuclear factor, Liver specific transcription factor LFB1, Maturity onset diabetes of the young 3 (MODY3), TCF1, Transcription factor 1 hepatic,HNF1A (Pancreatic Tumor Suppressor)
    Cellular localisation: Nuclear

    分子量

    79kDa

    基因ID

    6927, 654455

    UniProt

    P20823

    途径

    Hormone Transport, Carbohydrate Homeostasis
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