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Recombinant CD235a/GYPA 抗体

This 兔 单克隆 anti-CD235a/GYPA antibody (Clone GYPA-3219R) specifically detects CD235a/GYPA in IHC (f). The antibody is reactive with 人 samples.
产品编号 ABIN6937357
发货至: 中国
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Quick Overview for Recombinant CD235a/GYPA 抗体 (ABIN6937357)

抗原

See all CD235a/GYPA (GYPA) 抗体
CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This CD235a/GYPA antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

GYPA-3219R
  • 特异性

    Recognizes a sialoglycoprotein of 39 kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant full-length human GYPA protein

    亚型

    IgG
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Erythrocytes in any human tissues.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

    别名

    GYPA

    背景

    Blood group--MN locus, GPA, GPErik, GpMiIII, GPSAT, GYPA, MN sialoglycoprotein, MNS, PAS2, Sialoglycoprotein alpha,Glycophorin A / CD235a (Erythrocyte Marker)
    Cellular localisation: Cell surface

    分子量

    39kDa

    基因ID

    2993, 2994, 434973

    UniProt

    P02724

    途径

    Maintenance of Protein Location
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