GATA3 抗体 (AA 357-436)
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- 抗原 See all GATA3 抗体
- GATA3 (GATA Binding Protein 3 (GATA3))
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抗原表位
- AA 357-436
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This GATA3 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- GATA-3 is a zinc finger transcription factor and plays an important role in promoting and directing cell proliferation, development, and differentiation in many tissues and cell types. GATA-3 expression is primarily seen in breast and urothelial carcinomas.'Therefore, GATA3 antibody can be useful in the identification of unknown primary carcinoma when carcinomas of the breast or bladder are a possibility.
- 交叉反应 (详细)
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant fragment of human GATA3 protein (around aa 357-436) (exact sequence is proprietary)
- 克隆位点
- GATA3-2442
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product GATA3 Primary Antibody
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7 or T47D cells. Breast or Bladder Carcinoma.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- GATA3 (GATA Binding Protein 3 (GATA3))
- 别名
- GATA3 (GATA3 产品)
- 背景
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GATA3, GATA binding protein-3, GATA-binding factor 3, GATA3, HDR, HDRS, Transacting T-cell-specific transcription factor GATA-3,GATA-3 (Breast and Urothelial Marker)
Cellular localisation: Nuclear - 分子量
- 50kDa
- 基因ID
- 2625, 524134
- UniProt
- P23771
- 途径
- Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
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