Gastrin 抗体
Quick Overview for Gastrin 抗体 (ABIN6937296)
抗原
See all Gastrin (GAST) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Gastrin, is a hormone that normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets. Its primary function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. It also responsible for stimulating smooth muscle contraction and increasing blood circulation and water secretion in the stomach and intestine. Gastrin is regulated by epidermal growth factor in both mice and humans. Gastrin is excreted in excess by pancreatic tumors in the Zollinger-Ellison syndrome. Gastrin-Releasing Peptide (GRP) stimulates the release of gastrin as well as other gastrointestinal hormones and also acts as an autocrine growth factor for certain cell types. High levels of GRP are found in the human lung just after birth and levels decrease thereafter in parallel with the observed disease in a number of pulmonary neuroendocrine cells. GRP is known to promote lung tumorigenesis in model systems.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human GAST protein
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亚型
- IgG1 kappa
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anti-Gastrin (GAST) (AA 1-101) antibody
GAST 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gastrin (GAST) (C-Term) antibodyGAST 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Gastrin (GAST) (AA 77-92) antibodyGAST 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Gastrin (GAST) (AA 1-101) antibodyGAST 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7G5 unconjugated
anti-Gastrin (GAST) (Center) antibodyGAST 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Gastrin (GAST) (AA 52-101) antibodyGAST 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Gastrin (GAST) (AA 1-104) antibodyGAST 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gastrin (GAST) antibodyGAST 适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal GAST-2632 unconjugated
anti-Gastrin (GAST) antibodyGAST 适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal GAST-2631 unconjugated
anti-Gastrin (GAST) (AA 1-100) antibodyGAST 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA) Optimal dilution for a specific application should be determined.
Positive_Control: Human Pituitary or Stomach.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Gastrin (GAST)
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别名
- GAST
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背景
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Component II, GAS, Gast, Gastrin component I, Gastrin component II, Gastrin component III, Gastrin precursor, Gastrin-14, Gastrin-17, Gastrin-34, Gastrin-52, Gastrin-6, Gastrin-71,Gastrin
Cellular localisation: Secreted. -
分子量
- 2/4/14kDa
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基因ID
- 2520, 2681
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UniProt
- P01350
抗原
-
