Recombinant Frataxin 抗体 (AA 57-210)
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- 抗原 See all Frataxin (FXN) 抗体
- Frataxin (FXN)
- 抗体类型
- Recombinant Antibody
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抗原表位
- AA 57-210
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Frataxin antibody is un-conjugated
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应用范围
- ELISA, Coating (Coat)
- 特异性
- Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.
- 交叉反应 (详细)
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant human Frataxin protein fragment (around aa 57-210) (exact sequence is proprietary)
- 克隆位点
- RFXN-2124
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product FXN Primary Antibody
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- 应用备注
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Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA),Optimal dilution for a specific application should be determined.
Positive_Control: HepG2, HL-60 or HEK293 cells. Pancreas and Liver.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- Frataxin (FXN)
- 别名
- FXN (FXN 产品)
- 别名
- zgc:158218 antibody, LOC100284365 antibody, BcDNA:AT09528 antibody, CG8971 antibody, DFH antibody, Dfh antibody, Dmel\\CG8971 antibody, X25 antibody, dfh antibody, CyaY antibody, FA antibody, FARR antibody, FRDA antibody, RGD1565754 antibody, Frda antibody, frataxin antibody, fxn antibody, LOC100284365 antibody, TVAG_182150 antibody, fh antibody, FTX1 antibody, FXN antibody, Fxn antibody
- 背景
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CyaY, d-FXN, FARR, Frataxin mature form, Frataxin (81-210), FRDA, Friedreich ataxia protein, Fxn, i-FXN, m56-FXN, m78-FXN, m81-FXN, X25,Frataxin (Mitochondrial Marker)
Cellular localisation: Cytoplasmic (Mitochondria) - 分子量
- 14kDa
- 基因ID
- 2395, 20685
- UniProt
- Q16595
- 途径
- Transition Metal Ion Homeostasis, Regulation of Cell Size
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