Frataxin 抗体 (AA 57-210)
Quick Overview for Frataxin 抗体 (AA 57-210) (ABIN6937289)
抗原
See all Frataxin (FXN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 57-210
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特异性
- Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment of human Frataxin (FXN) protein (around aa 57-210) (exact sequence is proprietary)
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亚型
- IgG2b kappa
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anti-Frataxin (FXN) (AA 57-210) antibody
FXN 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal FXN-2124 unconjugated
anti-Frataxin (FXN) (AA 42-210) antibodyFXN 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Frataxin (FXN) (AA 91-200) antibodyFXN 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3G9 unconjugated
anti-Frataxin (FXN) (AA 91-200) antibodyFXN 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1D9 unconjugated
anti-Frataxin (FXN) (AA 41-207) antibodyFXN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Frataxin (FXN) (AA 36-64), (N-Term) antibodyFXN 适用: 人 WB 宿主: 兔 Polyclonal RB41914 unconjugated
anti-Frataxin (FXN) (AA 1-210) antibodyFXN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Frataxin (FXN) (AA 1-210) antibodyFXN 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Frataxin (FXN) (AA 105-154) antibodyFXN 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 犬, 豚鼠, 猴, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frataxin (FXN) (Internal Region) antibodyFXN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HepG2, Panc-2, HL-60 or HEK293 cells. Pancreas and Liver.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Frataxin (FXN)
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别名
- FXN
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背景
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CyaY, d-FXN, FARR, Frataxin mature form, Frataxin (81-210), FRDA, Friedreich ataxia protein, Fxn, i-FXN, m56-FXN, m78-FXN, m81-FXN, X25,Frataxin (Marker of Friedreich Ataxia)
Cellular localisation: Cytoplasmic (Mitochondria) -
分子量
- 14kDa
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基因ID
- 2395, 20685
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UniProt
- Q16595
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途径
- Transition Metal Ion Homeostasis, Regulation of Cell Size
抗原
-
