FUT3 抗体
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- 抗原 See all FUT3 抗体
- FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FUT3 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Lewis blood group antigens are carbohydrate moieties structurally integrated in mucous secretions. Lewis antigen system alterations have been described in gastric carcinoma and associated lesions. Anomalous expression of Lewis B antigen has been found in some non-secretory gastric carcinomas and colorectal cancers.
- 交叉反应 （详细）
- Human. Guinea Pig.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Mucin isolated from a human ovarian cyst fluid
- 克隆位点
- 2-25LE-same as LWB01
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product FUT3 Primary Antibody
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anti-Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3) (AA 199-361) antibody
FUT3 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 1F8G5C7 unconjugated
anti-Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3) (AA 83-187) antibodyFUT3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3) antibodyFUT3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3) (Internal Region) antibodyFUT3 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3) antibodyFUT3 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3) (AA 1-361) antibodyFUT3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3) antibodyFUT3 适用: 人, 豚鼠 IHC, IF, ISt, StM 宿主: 小鼠 Monoclonal 2-25LE-same as LWB01 unconjugated
anti-Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3) (AA 1-361) antibodyFUT3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3) (AA 278-327) antibodyFUT3 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3) (AA 1-100) antibodyFUT3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Colon.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))
- 别名
- FUT3 (FUT3 产品)
- 别名
- CD174 antibody, FT3B antibody, FucT-III antibody, LE antibody, Les antibody, fut356 antibody, FUT3 antibody, ATFUT3 antibody, F1M20.10 antibody, F1M20_10 antibody, fucosyltransferase 3 antibody, fucosyltransferase 3 (Lewis blood group) antibody, fucosyltransferase 3 (Lewis blood group) L homeolog antibody, fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) antibody, fucosyltransferase 3 antibody, galactoside 3(4)-L-fucosyltransferase antibody, FUT3 antibody, fut3.L antibody, fut3 antibody, LOC697452 antibody, LOC697582 antibody
- 背景
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Blood group Lewis alpha-4-fucosyltransferase, Fucosyltransferase 3, Fucosyltransferase III, FucT-III, FUT3, Galactoside 3(4)-L-fucosyltransferase, gastric mucin, leB, lewis antigen system, lewis B blood group antigen, Lewis FT, major airway glycoprotein,Blood Group Antigen Lewis B
Cellular localisation: Cytoplasmic - 分子量
- 45kDa
- 基因ID
- 2525, 169238
- UniProt
- P21217
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