FOXA1 抗体 (AA 372-472)
Our Local Distributor
北京 101111
Quick Overview for FOXA1 抗体 (AA 372-472) (ABIN6937254)
抗原
See all FOXA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 372-472
-
特异性
- The transcription factor Forkhead-box A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors.HNF-1 (), and HNF-6 compose, in part, a homeoprotein family designated the hepatocyte nuclear factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. FOXA1 is expressed in normal breast ductal epithelium and other epithelium in different organs, such as lung, pancreas, bladder, prostate, and colon. Recently, FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. FOXA1 expression correlates with estrogen receptor (ER)-positivity, especially in luminal subtype A breast cancers, which is associated with favorable prognosis. FOXA1 is useful in the sub-classification of breast carcinomas.
-
无交叉反应
- 大鼠
-
交叉反应 （详细）
- Human. Does not react with Rat.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Recombinant human FOXA1 protein fragment (aa372-472) (exact sequence is proprietary)
-
亚型
- IgG1 kappa
-
-
anti-Forkhead Box A1 (FOXA1) (C-Term) antibody
Verified FOXA1 适用: 人, 小鼠 WB, IF, FACS, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 367-472) antibodyFOXA1 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2D7 unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 367-472) antibodyFOXA1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B1 unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 372-472) antibodyFOXA1 适用: 人 WB, IHC, IF, FACS, ISt, StM 宿主: 小鼠 Monoclonal FOXA1-1512 unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 372-472) antibodyFOXA1 适用: 人, 大鼠 WB, IHC, StM 宿主: 小鼠 Monoclonal FOXA1-1518 unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 372-472) antibodyFOXA1 适用: 人, 大鼠 IHC, ISt, StM 宿主: 小鼠 Monoclonal FOXA1-1241 unconjugated
anti-Forkhead Box A1 (FOXA1) (C-Term) antibodyFOXA1 适用: 人 WB, IF, IHC (p), ICC, IP, ChIP, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 263-472) antibodyFOXA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 367-472) antibodyFOXA1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4F6 unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 367-472) antibodyFOXA1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3C1 unconjugated
-
-
应用备注
-
Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, PC3, HepG-2 or MCF-7 cells. Human liver, pancreas or prostate tissue.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- FOXA1 (Forkhead Box A1 (FOXA1))
-
别名
- FOXA1
-
背景
-
Forkhead box protein A1 (FOXA1), Hepatocyte nuclear factor 3-alpha (HNF-3-alpha or HNF-3A or HNF3A), Transcription factor 3A (TCF-3A or TCF3A),FOXA1 / HNF3A
Cellular localisation: Nuclear -
分子量
- 49kDa
-
基因ID
- 3169, 163484
-
UniProt
- P55317
-
途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis
抗原
-
