FGA 抗体
Quick Overview for FGA 抗体 (ABIN6937227)
抗原
See all FGA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits: . Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Human acute monoblastic leukemia cells.
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亚型
- IgM kappa
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应用备注
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Known_Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: Plasma.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Purified Ab WITHOUT BSA at 1.0mg/ml
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- FGA (Fibrinogen alpha Chain (FGA))
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别名
- FGA
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背景
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Ac1873, Fba5e, FGA, Fib, Fib2, Fibrinogen alpha chain, Fibrinogen, A alpha polypeptide, Fibrinogen--alpha polypeptide chain, Fibrinopeptide A,Fibrinogen Alpha Chain
Cellular localisation: Secreted. -
分子量
- 30kDa
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基因ID
- 2243, 351593
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UniProt
- P02671
抗原
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