Ezrin 抗体
Quick Overview for Ezrin 抗体 (ABIN6937202)
抗原
See all Ezrin (EZR) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Ezrin, Moesin and Radixin belong to a family of highly homologous actin-associated proteins that are localized just beneath the plasma membrane. The proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins. Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases, including the epidermal growth factor receptor. Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78. Moesin and Radixin share over 70 % homology with Ezrin and are co-expressed within various cell types. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation. Overexpression of Ezrin predicts the poor prognosis of gastric adenocarcinoma.
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交叉反应 （详细）
- Human. Others-not tested.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human full-length Ezrin protein
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亚型
- IgG2b kappa
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anti-Ezrin (EZR) (AA 292-464) antibody
EZR 适用: 人, 小鼠, 猴 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6F1A9 unconjugated
anti-Ezrin (EZR) (AA 1-295) antibodyEZR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ezrin (EZR) (AA 1-586) antibodyEZR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Ezrin (EZR) (pTyr478) antibodyEZR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ezrin (EZR) (AA 1-586) antibodyEZR 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1E11 unconjugated
anti-Ezrin (EZR) antibodyEZR 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal CPTC-Ezrin-1 unconjugated
anti-Ezrin (EZR) (pTyr353) antibodyEZR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ezrin (EZR) (AA 350-470) antibodyEZR 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Ezrin (EZR) (AA 455-586) antibodyEZR 适用: 人, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ezrin (EZR) (AA 1-251) antibodyEZR 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Western Blotting (1-2 μg/mL), ,Immunohistology (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: SKBr3, HeLa, HEK293, MCF-7, Jurkat, A431, MCF-7. Cerebral cortex and hippocampus.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Ezrin (EZR)
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别名
- Ezrin
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背景
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Villin-2, CVIL, Epididymis secretory protein Li 105, EZR, p81, VIL2, Cytovillin, Cytovillin 2, HEL S 105, DKFZp762H157,Ezrin / p81
Cellular localisation: Cell Surface -
分子量
- 87kDa
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基因ID
- 7430, 487027
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UniProt
- P15311
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途径
- Maintenance of Protein Location
抗原
-
