ENAH 抗体 (AA 485-589)
Quick Overview for ENAH 抗体 (AA 485-589) (ABIN6937147)
抗原
See all ENAH 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 485-589
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特异性
- The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. WASP is a downstream effector of Cdc42 and has been implicated in actin polymerization and cyto- skeletal organization. Distantly related proteins, VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), are involved in the regulation of cytoskeletal dynamics. Both Mena and VASP accumulate at focal adhesions. Mena is highly expressed in the developing nervous system and may be involved in growth cone motility and axon guidance.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment of human MENA protein (around aa 485-589) (exact sequence is proprietary)
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亚型
- IgG2c kappa
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anti-Enabled Homolog (ENAH) (AA 291-390) antibody
ENAH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E6 unconjugated
anti-Enabled Homolog (ENAH) (AA 485-589) antibodyENAH 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal ENAH-1988 unconjugated
anti-Enabled Homolog (ENAH) (AA 412-591) antibodyENAH 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Enabled Homolog (ENAH) (Internal Region) antibodyENAH 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Enabled Homolog (ENAH) (C-Term) antibodyENAH 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Enabled Homolog (ENAH) antibodyENAH 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Enabled Homolog (ENAH) (AA 671-720) antibodyENAH 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Enabled Homolog (ENAH) (C-Term) antibodyENAH 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Enabled Homolog (ENAH) (AA 472-521) antibodyENAH 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7 cells. Uterus.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- ENAH (Enabled Homolog (ENAH))
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别名
- ENAH
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背景
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ENA, ENAH, MENA, NDPP1,ENAH / MENA (Actin Regulator)
Cellular localisation: Cytoplasmic -
分子量
- 80/88/140kDa
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基因ID
- 55740, 497893
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UniProt
- Q8N8S7
抗原
-
