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Recombinant Elastin 抗体

This anti-Elastin antibody is a 兔 单克隆 antibody detecting Elastin in IHC (f). Suitable for 人.
产品编号 ABIN6937144
发货至: 中国

Quick Overview for Recombinant Elastin 抗体 (ABIN6937144)

抗原

See all Elastin (ELN) 抗体
Elastin (ELN)

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This Elastin antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

ELN-3131R
  • 特异性

    Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries.It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticityto the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant full-length human Elastin protein

    亚型

    IgG
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: A549 or U-2197 cells. Liver, Kidney, Lung or Intestine.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    Elastin (ELN)

    别名

    ELN

    背景

    Elastin, ELN, SVAS, Tropoelastin, WBS, WS,Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis)
    Cellular localisation: Secreted and Extracellular Space

    分子量

    70kDa

    基因ID

    2006, 647061

    UniProt

    P15502

    途径

    Regulation of Actin Filament Polymerization
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