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Elastin 抗体

ELN 适用: 人 ELISA, Coat, IHC (f) 宿主: 小鼠 Monoclonal ELN-1981 unconjugated
产品编号 ABIN6937143
发货至: 中国
  • 抗原 See all Elastin (ELN) 抗体
    Elastin (ELN)
    适用
    • 56
    • 24
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    • 1
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    宿主
    • 51
    • 14
    小鼠
    克隆类型
    • 48
    • 17
    单克隆
    标记
    • 32
    • 7
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    • 3
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    • 3
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    This Elastin antibody is un-conjugated
    应用范围
    • 29
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    • 14
    • 14
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    ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries.It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticityto the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human Elastin protein
    克隆位点
    ELN-1981
    亚型
    IgG1 kappa
    Top Product
    Discover our top product ELN Primary Antibody
  • 应用备注

    Known_Application: ELISA (For coating, order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: A549 or U-2197 cells. Liver, Kidney, Lung or Intestine.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    Elastin (ELN)
    别名
    ELN (ELN 产品)
    别名
    SVAS antibody, WBS antibody, WS antibody, AI385707 antibody, AI480567 antibody, E030024M20Rik antibody, RATTREL11 antibody, TREL11 antibody, Trela antibody, Trela26 antibody, ELN antibody, elastin antibody, ELN antibody, Eln antibody, LOC574132 antibody, Tcur_2481 antibody, Kfla_2289 antibody, LOC100620140 antibody
    背景
    Elastin, ELN, SVAS, Tropoelastin, WBS, WS,Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis)
    Cellular localisation: Secreted and Extracellular Space
    分子量
    70kDa
    基因ID
    2006, 647061
    UniProt
    P15502
    途径
    Regulation of Actin Filament Polymerization
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