Elastin 抗体
Quick Overview for Elastin 抗体 (ABIN6937143)
抗原
See all Elastin (ELN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries.It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticityto the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human Elastin protein
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亚型
- IgG1 kappa
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anti-Elastin (ELN) (AA 681-786) antibody
ELN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Elastin (ELN) (AA 392-645) antibodyELN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Elastin (ELN) (AA 266-443) antibodyELN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Elastin (ELN) antibodyELN 适用: 人 IHC, StM 宿主: 兔 Monoclonal ELN-3131R unconjugated Recombinant Antibody
anti-Elastin (ELN) antibodyELN 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal ELN-1981 unconjugated
anti-Elastin (ELN) antibodyELN 适用: 人 IHC, ELISA, IHC (p), IF, RIA 宿主: 兔 Polyclonal unconjugated
anti-Elastin (ELN) antibodyELN 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-648R unconjugated Recombinant Antibody
anti-Elastin (ELN) (AA 392-645) antibodyELN 适用: 人 WB 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Elastin (ELN) antibodyELN 适用: 人, 小鼠, Cow, 小鸡 WB, IHC, IP, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 10B8 unconjugated
anti-Elastin (ELN) (AA 27-200) antibodyELN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: ELISA (For coating, order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: A549 or U-2197 cells. Liver, Kidney, Lung or Intestine.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Elastin (ELN)
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别名
- ELN
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背景
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Elastin, ELN, SVAS, Tropoelastin, WBS, WS,Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis)
Cellular localisation: Secreted and Extracellular Space -
分子量
- 70kDa
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基因ID
- 2006, 647061
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UniProt
- P15502
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途径
- Regulation of Actin Filament Polymerization
抗原
-
