电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

RCAS1 抗体

EBAG9 适用: 人 IF, IHC (f) 宿主: 小鼠 Monoclonal CPTC-EBAG9-1 unconjugated
产品编号 ABIN6937120
发货至: 中国
  • 抗原 See all RCAS1 (EBAG9) 抗体
    RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))
    适用
    • 36
    • 32
    • 13
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 41
    • 8
    • 2
    小鼠
    克隆类型
    • 42
    • 9
    单克隆
    标记
    • 25
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RCAS1 antibody is un-conjugated
    应用范围
    • 22
    • 16
    • 13
    • 13
    • 9
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    EBAG9, also known as RCAS1, is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers, including uterine, ovarian, and lung cancer cells, and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis, contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant human full-length EBAG9 protein
    克隆位点
    CPTC-EBAG9-1
    亚型
    IgG2c kappa
    Top Product
    Discover our top product EBAG9 Primary Antibody
  • 应用备注

    Known_Application: Immunofluorescence (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: MCF-7, Jurkat, 293 cell lysates, Human skeletal muscle tissue.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))
    别名
    EBAG9 (EBAG9 产品)
    别名
    EB9 antibody, PDAF antibody, MGC56608 antibody, zgc:56608 antibody, MGC84425 antibody, EBAG9 antibody, AI835379 antibody, Rcas1 antibody, RCAS1 antibody, eb9 antibody, pdaf antibody, rcas1 antibody, estrogen receptor binding site associated, antigen, 9 antibody, estrogen receptor binding site associated, antigen, 9 L homeolog antibody, estrogen receptor-binding fragment-associated gene 9 antibody, EBAG9 antibody, ebag9 antibody, ebag9.L antibody, Ebag9 antibody
    背景
    BAG9, cancer associated surface antigen, cancer associated surface antigen RCAS1, EB9, estrogen receptor binding fragment associated gene 9, PDAF, receptor binding cancer antigen expressed on SiSo cells,RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9
    Cellular localisation: Golgi apparatus.
    分子量
    32kDa
    基因ID
    9166, 409368
    UniProt
    O00559
You are here:
客服