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DPP4 抗体

This anti-DPP4 antibody is a 小鼠 单克隆 antibody detecting DPP4 in FACS, IHC (fro) 和 IF. Suitable for 人.
产品编号 ABIN6937102
发货至: 中国

Quick Overview for DPP4 抗体 (ABIN6937102)

抗原

See all DPP4 抗体
DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This DPP4 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

克隆位点

202-36
  • 特异性

    Recognizes a glycoprotein of 110 kDa, identified as CD26 (Workshop VI, Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this MAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.

    无交叉反应

    猪, 绵羊

    交叉反应 (详细)

    Human. Rat. Does not react with Pig or Sheep.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Human T cell clone

    亚型

    IgG2b kappa
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Frozen Only) (1-2 μg/mL for 30 minutes at RT) Optimal dilution for a specific application should be determined.

    Positive_Control: YT, HEP-G2 cells and lymphocytes. Lymph nodes and tonsils.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

    别名

    DPP4

    背景

    ADA-binding protein (ADABP), Adenosine deaminase complexing protein 2 (ADCP-2), Dipeptidyl peptidase 4, Dipeptidyl peptidase 4 soluble form, Dipeptidyl peptidase IV membrane form, Dipeptidyl peptidase IV soluble form, Dipeptidyl peptidase, intestinal, Dipeptidylpeptidase 4, Dipeptidylpeptidase IV, DPP4, DPPIV, Intestinal dipeptidyl peptidase, T-cell activation antigen CD26, TP103,CD26 (DPP IV / ADA-Binding Protein)
    Cellular localisation: Cell Surface

    分子量

    110kDa

    基因ID

    1803, 368912

    UniProt

    P27487

    途径

    Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
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