电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

DBN1 抗体 (AA 150-281)

DBN1 适用: 人 WB, IHC (f) 宿主: 小鼠 Monoclonal DBN1-2879 unconjugated
产品编号 ABIN6937083
发货至: 中国
  • 抗原 See all DBN1 抗体
    DBN1 (Drebrin 1 (DBN1))
    抗原表位
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-281
    适用
    • 36
    • 20
    • 19
    • 1
    • 1
    宿主
    • 28
    • 8
    • 1
    小鼠
    克隆类型
    • 28
    • 9
    单克隆
    标记
    • 21
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DBN1 antibody is un-conjugated
    应用范围
    • 34
    • 13
    • 13
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2), and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant fragment (aa 150-281) of human DBN1 protein (exact sequence is proprietary)
    克隆位点
    DBN1-2879
    亚型
    IgG1 kappa
    Top Product
    Discover our top product DBN1 Primary Antibody
  • 应用备注

    Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: PC3 cells. Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    DBN1 (Drebrin 1 (DBN1))
    别名
    DBN1 (DBN1 产品)
    别名
    D0S117E antibody, DBN1 antibody, LOC733967 antibody, drebrin 1 antibody, drebrin 1 S homeolog antibody, DBN1 antibody, Dbn1 antibody, dbn1.S antibody, dbn1 antibody
    背景
    Developmentally regulated brain protein, Drebrin 1, Drebrin, Drebrin E, Drebrin E2, Drebrin1, DrebrinE,Drebrin 1 (DBN1)
    Cellular localisation: Cytoplasmic
    分子量
    120kDa
    基因ID
    1627, 130316
    UniProt
    Q16643
    途径
    Maintenance of Protein Location
You are here:
客服