DBN1 抗体 (AA 150-281)
Quick Overview for DBN1 抗体 (AA 150-281) (ABIN6937083)
抗原
See all DBN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 150-281
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特异性
- Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2), and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment (aa 150-281) of human DBN1 protein (exact sequence is proprietary)
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亚型
- IgG1 kappa
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anti-Drebrin 1 (DBN1) (AA 150-281) antibody
DBN1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal DBN1-2879 unconjugated
anti-Drebrin 1 (DBN1) (AA 1-326) antibody (PE)DBN1 适用: 人 ICFC 宿主: 小鼠 Monoclonal DBN-N-03 PE
anti-Drebrin 1 (DBN1) (Internal Region) antibodyDBN1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 1-649) antibodyDBN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E11 unconjugated
anti-Drebrin 1 (DBN1) (AA 1-326) antibodyDBN1 适用: 人 WB, FACS, MS 宿主: 小鼠 Monoclonal DBN-N-03 unconjugated
anti-Drebrin 1 (DBN1) (AA 401-596) antibodyDBN1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 350-649) antibodyDBN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 3-134) antibodyDBN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 151-250) antibodyDBN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Drebrin 1 (DBN1) (AA 194-228) antibodyDBN1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB56246 unconjugated
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应用备注
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Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: PC3 cells. Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- DBN1 (Drebrin 1 (DBN1))
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别名
- DBN1
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背景
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Developmentally regulated brain protein, Drebrin 1, Drebrin, Drebrin E, Drebrin E2, Drebrin1, DrebrinE,Drebrin 1 (DBN1)
Cellular localisation: Cytoplasmic -
分子量
- 120kDa
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基因ID
- 1627, 130316
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UniProt
- Q16643
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途径
- Maintenance of Protein Location
抗原
-
