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Cytokeratin 1 抗体

KRT1 适用: 人 WB, IHC, FACS, IF, StM 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6937073
发货至: 中国
  • 抗原 See all Cytokeratin 1 (KRT1) 抗体
    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
    适用
    • 92
    • 56
    • 43
    • 24
    • 16
    • 13
    • 9
    • 8
    • 7
    • 5
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    • 1
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    宿主
    • 76
    • 38
    克隆类型
    • 68
    • 46
    多克隆
    标记
    • 46
    • 15
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    This Cytokeratin 1 antibody is un-conjugated
    应用范围
    • 79
    • 50
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    • 27
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    • 26
    • 17
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    • 14
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    • 8
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    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Staining Methods (StM)
    特异性
    Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which 67 kDa (CK1), 64 kDa (CK3), 59 kDa (CK4), 58 kDa (CK5), 56 kDa (CK6), 52 kDa (CK8), 56.5 kDa (CK10), 50 kDa (CK14), 50 kDa (CK15), 48 kDa (CK16), 40 kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. It is a broad spectrum anti pan-cytokeratin antibody, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It may be useful to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has high sensitivity in the recognition of epithelial cells and carcinomas.
    交叉反应 (详细)
    Expected to show broad species reactivity.
    免疫原
    Recombinant full-length human KRT76 and KRT77 proteins
    亚型
    IgG
    Top Product
    Discover our top product KRT1 Primary Antibody
  • 应用备注

    Positive Control: Skin, Adeno- or Squamous carcinomas.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1 μg/mL for 2 hours at RT), Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 缓冲液
    10 mM PBS without BSA and without Azide.
    储存液
    Azide free
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.
    有效期
    24 months
  • 抗原
    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
    别名
    Cytokeratin (KRT1 产品)
    别名
    CK1 antibody, EHK antibody, EHK1 antibody, EPPK antibody, K1 antibody, KRT1A antibody, NEPPK antibody, Krt-2.1 antibody, Krt2-1 antibody, Krt86 antibody, KRT1 antibody, Kb1 antibody, KER1 antibody, CK-1 antibody, Keratin-1 antibody, keratin 1 antibody, KRT1 antibody, Krt1 antibody
    分子量
    40-67kDa
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