Cytokeratin 1 抗体
Quick Overview for Cytokeratin 1 抗体 (ABIN6937073)
抗原
See all Cytokeratin 1 (KRT1) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which 67 kDa (CK1), 64 kDa (CK3), 59 kDa (CK4), 58 kDa (CK5), 56 kDa (CK6), 52 kDa (CK8), 56.5 kDa (CK10), 50 kDa (CK14), 50 kDa (CK15), 48 kDa (CK16), 40 kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. It is a broad spectrum anti pan-cytokeratin antibody, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It may be useful to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has high sensitivity in the recognition of epithelial cells and carcinomas.
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交叉反应 （详细）
- Expected to show broad species reactivity.
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免疫原
- Recombinant full-length human KRT76 and KRT77 proteins
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亚型
- IgG
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anti-Keratin 1 (KRT1) (AA 141-240) antibody
KRT1 适用: 人, 大鼠, 小鼠, Cow WB, FACS, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 1 (KRT1) antibodyKRT1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Keratin 1 (KRT1) (AA 101-200) antibodyKRT1 适用: 人, 小鼠, 马 WB, FACS, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 1 (KRT1) (AA 487-644) antibodyKRT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 1 (KRT1) (AA 189-497) antibodyKRT1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 1 (KRT1) (AA 267-438) antibodyKRT1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 1 (KRT1) (C-Term) antibodyKRT1 适用: 人, 大鼠 IHC, StM 宿主: 小鼠 Monoclonal LHK1 unconjugated
anti-Keratin 1 (KRT1) (AA 415-443) antibodyKRT1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18411 unconjugated
anti-Keratin 1 (KRT1) antibodyKRT1 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Monoclonal 1C2 unconjugated
anti-Keratin 1 (KRT1) (AA 387-496) antibodyKRT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Positive Control: Skin, Adeno- or Squamous carcinomas.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1 μg/mL for 2 hours at RT), Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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缓冲液
- 10 mM PBS without BSA and without Azide.
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储存液
- Azide free
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.
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有效期
- 24 months
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- Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
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别名
- Cytokeratin
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分子量
- 40-67kDa
抗原
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