Cathepsin K 抗体 (AA 163-274)
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- 抗原 See all Cathepsin K (CTSK) 抗体
- Cathepsin K (CTSK)
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抗原表位
- AA 163-274
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Cathepsin K antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.
- 交叉反应 (详细)
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant fragment of human Cathepsin K protein (around aa 163-274) (exact sequence is proprietary)
- 克隆位点
- CTSK-2791
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CTSK Primary Antibody
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Human liver or breast tissue (IHC).
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- Cathepsin K (CTSK)
- 别名
- CTSK (CTSK 产品)
- 别名
- CTS02 antibody, CTSO antibody, CTSO1 antibody, CTSO2 antibody, PKND antibody, PYCD antibody, AI323530 antibody, MMS10-Q antibody, Ms10q antibody, catK antibody, CTSK antibody, wu:fa95f03 antibody, wu:fb08b05 antibody, zgc:110367 antibody, cts02 antibody, ctso antibody, ctso1 antibody, ctso2 antibody, pknd antibody, pycd antibody, OC-2 antibody, catk antibody, cathepsin K antibody, cathepsin K L homeolog antibody, Cathepsin K antibody, CTSK antibody, Ctsk antibody, ctsk antibody, ctsk.L antibody, catk antibody
- 背景
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Cathepsin K, Cathepsin O, Cathepsin O1, Cathepsin O2, Cathepsin X, CTS02, Ctsk, CTSO1, CTSO2, PKND, PYCD,Cathepsin K (Marker of Tumor Invasiveness)
Cellular localisation: Cytoplasmic - 分子量
- 39kDa
- 基因ID
- 1513, 632466
- UniProt
- P43235
- 途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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