Cathepsin K 抗体 (AA 163-274)
Quick Overview for Cathepsin K 抗体 (AA 163-274) (ABIN6937059)
抗原
See all Cathepsin K (CTSK) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 163-274
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特异性
- The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment of human Cathepsin K protein (around aa 163-274) (exact sequence is proprietary)
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亚型
- IgG1 kappa
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anti-Cathepsin K (CTSK) (AA 54-317) antibody
CTSK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin K (CTSK) (AA 163-274) antibodyCTSK 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CTSK-2791 unconjugated
anti-Cathepsin K (CTSK) (AA 220-329) antibodyCTSK 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Cathepsin K (CTSK) (AA 115-329) antibodyCTSK 适用: 人 WB 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Cathepsin K (CTSK) (AA 71-319) antibodyCTSK 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin K (CTSK) (AA 115-329) antibodyCTSK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin K (CTSK) (AA 220-331) antibodyCTSK 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Cathepsin K (CTSK) (AA 115-329) antibodyCTSK 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin K (CTSK) (N-Term) antibodyCTSK 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin K (CTSK) (AA 97-126) antibodyCTSK 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19253 unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Human liver or breast tissue (IHC).
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Cathepsin K (CTSK)
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别名
- CTSK
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背景
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Cathepsin K, Cathepsin O, Cathepsin O1, Cathepsin O2, Cathepsin X, CTS02, Ctsk, CTSO1, CTSO2, PKND, PYCD,Cathepsin K (Marker of Tumor Invasiveness)
Cellular localisation: Cytoplasmic -
分子量
- 39kDa
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基因ID
- 1513, 632466
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UniProt
- P43235
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
-
