Cathepsin D 抗体 (AA 104-250)
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- 抗原 See all Cathepsin D (CTSD) 抗体
- Cathepsin D (CTSD)
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抗原表位
- AA 104-250
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Cathepsin D antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 52kDa preprocathepsin D that is cleaved and glycosylated to form a 48kDa procathepsin D and then further cleaved to produce 34kDa and 14kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant fragment of human Cathepsin D protein (around aa 104-250) (exact sequence is proprietary)
- 克隆位点
- CTSD-2781
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CTSD Primary Antibody
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anti-Cathepsin D (CTSD) (C-Term) antibody
CTSD 适用: 人, 小鼠, 大鼠, Hamster, 猴, Pig, 犬, 马, 兔, Cow, 豚鼠, Cat, Avian, 小鸡, 驴, 山羊, 绵羊 WB, IHC (p), IF, IHC (fro), IEM 宿主: 山羊 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 66-410) antibodyCTSD 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 1-412) antibodyCTSD 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 104-250) antibodyCTSD 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CTSD-3082 unconjugated
anti-Cathepsin D (CTSD) (AA 26-412) antibodyCTSD 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 3F12-1B9 unconjugated
anti-Cathepsin D (CTSD) (AA 21-412) antibodyCTSD 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C9 unconjugated
anti-Cathepsin D (CTSD) (AA 120-407) antibodyCTSD 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 104-250) antibodyCTSD 适用: 人 IHC, IF, StM 宿主: 小鼠 Monoclonal CTSD-3276 unconjugated
anti-Cathepsin D (CTSD) (C-Term) antibodyCTSD 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 豚鼠, Saccharomyces cerevisiae, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin D (CTSD) (AA 101-200) antibodyCTSD 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: K-562, MCF-7 or SK-BR3 cells. Human kidney, liver, lung or breast tissues.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- Cathepsin D (CTSD)
- 别名
- CTSD (CTSD 产品)
- 别名
- catD antibody, fb93e11 antibody, fj17b09 antibody, wu:fb93e11 antibody, wu:fj17b09 antibody, LOC398557 antibody, Cathd antibody, CatD antibody, LOC100136761 antibody, CTSD antibody, DKFZp469J0315 antibody, DDBDRAFT_0205785 antibody, DDBDRAFT_0215012 antibody, DDB_0205785 antibody, DDB_0215012 antibody, CLN10 antibody, CPSD antibody, CD antibody, cathepsin D antibody, cathepsin D S homeolog antibody, lysosomal aspartic protease antibody, cathepsin D-like antibody, ctsd antibody, LOC398557 antibody, ctsd.S antibody, CatD antibody, LOC5567565 antibody, LOC100136761 antibody, CTSD antibody, Cathd antibody, ctsD antibody, catd antibody, Ctsd antibody, LOC443060 antibody
- 背景
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CatD, Cathepsin D, Ceroid lipofuscinosis neuronal 10, CLN10, CPSD, Epididymis secretory sperm binding protein Li 130P, Lysosomal aspartyl peptidase, Lysosomal aspartyl protease,Cathepsin D (Tumor Marker)
Cellular localisation: Cytoplasmic - 分子量
- 48kDa (Procathepsin D), 34kDa (Cathepsin D), 14kDa (Cathepsin D)
- 基因ID
- 1509, 654447
- UniProt
- P07339
- 途径
- Peptide Hormone Metabolism
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