CPA1 抗体
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北京 101111
Quick Overview for CPA1 抗体 (ABIN6937013)
抗原
See all CPA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Carboxypeptidase A1 / CPA1 (Pancreatic Cancer Marker) Antibody
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特异性
- Human pancreatic procarboxypeptidase A exists as three different active forms, two of which are designated carboxypeptidase A1 (CPA1) and carboxypeptidase A2 (CPA2). CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase, CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Via its catalytic activity, CPA1 is also thought to be involved in zymogen (proenzyme) inhibition, probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events.
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交叉反应 （详细）
- Human.
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纯化方法
- 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system.
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免疫原
- Recombinant full-length human CPA1 protein
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亚型
- IgG1, kappa
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anti-Carboxypeptidase A1 (Pancreatic) (CPA1) (AA 205-419) antibody
CPA1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase A1 (Pancreatic) (CPA1) antibodyCPA1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal CPA1-2711 unconjugated
anti-Carboxypeptidase A1 (Pancreatic) (CPA1) antibodyCPA1 适用: 人, 犬 WB, IHC 宿主: 小鼠 Monoclonal CPA1-2714 unconjugated
anti-Carboxypeptidase A1 (Pancreatic) (CPA1) (AA 1-419) antibodyCPA1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase A1 (Pancreatic) (CPA1) (AA 1-419) antibodyCPA1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3F11 unconjugated
anti-Carboxypeptidase A1 (Pancreatic) (CPA1) (full length) antibodyCPA1 适用: 人 IHC 宿主: 小鼠 Monoclonal 601M unconjugated
anti-Carboxypeptidase A1 (Pancreatic) (CPA1) (Internal Region) antibodyCPA1 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase A1 (Pancreatic) (CPA1) (AA 201-300) antibodyCPA1 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase A1 (Pancreatic) (CPA1) (AA 111-419) antibodyCPA1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase A1 (Pancreatic) (CPA1) antibody (APC)CPA1 适用: 人 IF, FACS 宿主: 小鼠 Monoclonal CA2 APC
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应用备注
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Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Pancreas. Pancreas tissue lysate.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- CPA1 (Carboxypeptidase A1 (Pancreatic) (CPA1))
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别名
- CPA1
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背景
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Carboxypeptidase A1 (pancreatic), CPA1, Pancreatic Carboxypeptidase A1, Procarboxypeptidase A1 pancreatic
Pancreas. Pancreas tissue lysate.
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分子量
- 47kDa
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基因ID
- 1357, 2879
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UniProt
- P15085
抗原
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