Complement 3d (C3d) (Acute Humoral Rejection Marker) 抗体
This anti- antibody is a 小鼠 单克隆 antibody detecting in Coat 和 ELISA. Suitable for 人.
Quick Overview for Complement 3d (C3d) (Acute Humoral Rejection Marker) 抗体 (ABIN6937012)
抗原
Complement 3d (C3d) (Acute Humoral Rejection Marker)
适用
人
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Coating (Coat), ELISA
克隆位点
C3D-2891
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纯化方法
- Purified by Protein A/G
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免疫原
- Recombinant full-length human Complement C3 protein
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亚型
- IgG2b kappa
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anti-Complement 3d (C3d) (Acute Humoral Rejection Marker) antibody
适用: 人 Coat, ELISA 宿主: 小鼠 Monoclonal C3D-2891 unconjugated
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应用备注
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Positive Control: Human kidney or rejected renal transplant tissue.
Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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缓冲液
- 10 mM PBS without BSA and without Azide.
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储存液
- Azide free
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.
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有效期
- 24 months
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- Complement 3d (C3d) (Acute Humoral Rejection Marker)
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背景
- The complement component proteins, C2, C3, C4 and C5, are potent anaphylatoxins that are released during complement activation. Binding of these proteins to their respective G protein-coupled receptors, C3aR, C1R and C5aR, induces proinflammatory events, such as cellular degranulation, smooth muscle contraction, arachidonic acid metabolism, cytokine release, leukocyte activation and cellular chemotaxis. C3d is a terminal degradation product of C3 that plays an important role in modulation of the adaptive immune response through the interaction with complement receptor type 2 (CR2). CR2 is important in the switched-isotype, high-affinity and memory humoral immune responses to T-dependent foreign antigens, as well as in the development of the natural antibody repertoire. This pH - and ionic strength-dependent association of C3d with CR2 represents a link between innate and adaptive immunity.
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分子量
- 35kDa (predicted)
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基因ID
- 718
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UniProt
- P01024
抗原
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