Chromogranin A 抗体
Quick Overview for Chromogranin A 抗体 (ABIN6936984)
抗原
See all Chromogranin A (CHGA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
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无交叉反应
- 大鼠
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交叉反应 （详细）
- Human. Does not react with Rat.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human chromogranin A protein
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亚型
- IgG2a kappa
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anti-Chromogranin A (CHGA) (AA 15-148) antibody
CHGA 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chromogranin A (CHGA) (AA 24-154) antibodyCHGA 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chromogranin A (CHGA) antibodyCHGA 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CGA-413 unconjugated
anti-Chromogranin A (CHGA) (AA 278-457) antibodyCHGA 适用: 人 IHC, FACS, WB, ELISA 宿主: 小鼠 Monoclonal 5H10B12 unconjugated
anti-Chromogranin A (CHGA) (AA 87-252) antibodyCHGA 适用: 人 FACS, WB, ELISA, ICC 宿主: 小鼠 Monoclonal 1A6B6 unconjugated
anti-Chromogranin A (CHGA) (AA 17-446) antibodyCHGA 适用: Pig IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chromogranin A (CHGA) (AA 278-457) antibodyCHGA 适用: 人 IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 1B7A4 unconjugated
anti-Chromogranin A (CHGA) antibodyCHGA 适用: 人, 小鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Chromogranin A (CHGA) antibodyCHGA 适用: 人, 大鼠, 小鼠, 猴, Pig IHC, StM 宿主: 小鼠 Monoclonal LK2H10 unconjugated
anti-Chromogranin A (CHGA) antibodyCHGA 适用: 人 IHC, StM 宿主: 兔 Monoclonal CHGA-1731R unconjugated Recombinant Antibody
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: PC12 cells. Adrenal gland, bowel, thyroid, pancreas or pheochromocytoma.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Chromogranin A (CHGA)
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别名
- CHGA
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背景
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Beta-Granin, CGA, CHGA, Chromogranin A Parathyroid Secretory Protein 1, ER-37, Pancreastatin, Parastatin, Parathyroid Secretory Protein 1, Pituitary Secretory Protein I, SP-I, Vasostatin I or II,Chromogranin A / CHGA (Neuroendocrine Marker)
Cellular localisation: Finely granular cytoplasmic -
分子量
- 68-75kDa
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基因ID
- 1113, 150793
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UniProt
- P10645
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途径
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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