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Recombinant Chromogranin A 抗体

CHGA 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal rCHGA-413 unconjugated Recombinant Antibody
产品编号 ABIN6936979
发货至: 中国
  • 抗原 See all Chromogranin A (CHGA) 抗体
    Chromogranin A (CHGA)
    抗体类型
    Recombinant Antibody
    适用
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    宿主
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    小鼠
    克隆类型
    • 123
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    单克隆
    标记
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    This Chromogranin A antibody is un-conjugated
    应用范围
    • 113
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    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
    无交叉反应
    大鼠
    交叉反应 (详细)
    Human. Does not react with Rat.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human CHGA protein.
    克隆位点
    RCHGA-413
    亚型
    IgG2b kappa
    Top Product
    Discover our top product CHGA Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: PC12 cells. Adrenal gland, bowel, thyroid, pancreas or pheochromocytoma.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    Chromogranin A (CHGA)
    别名
    CHGA (CHGA 产品)
    别名
    CGA antibody, CG-ALPHA antibody, FSHA antibody, GPHA1 antibody, GPHa antibody, HCG antibody, LHA antibody, TSHA antibody, ChrA antibody, fj05f09 antibody, si:dkey-177p2.2 antibody, wu:fj05f09 antibody, zgc:101749 antibody, zgc:56075 antibody, CHGA antibody, cgA antibody, chga antibody, chromogranin A antibody, glycoprotein hormones, alpha polypeptide antibody, uncharacterized CHGA antibody, chromogranin A S homeolog antibody, CHGA antibody, CGA antibody, Chga antibody, chga antibody, chga.S antibody
    背景
    Beta-Granin, CGA, CHGA, Chromogranin A Parathyroid Secretory Protein 1, ER-37, Pancreastatin, Parastatin, Parathyroid Secretory Protein 1, Pituitary Secretory Protein I, SP-I, Vasostatin I or II,Chromogranin A / CHGA (Neuroendocrine Marker)
    Cellular localisation: Finely granular cytoplasmic
    分子量
    68-75kDa
    基因ID
    1113, 150793
    UniProt
    P10645
    途径
    Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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