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CGB 抗体

CGB 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal HCGb-54 unconjugated
产品编号 ABIN6936963
发货至: 中国
  • 抗原 See all CGB 抗体
    CGB (Chorionic Gonadotropin, beta Polypeptide (CGB))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CGB antibody is un-conjugated
    应用范围
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    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    This MAb reacts with a protein of 22 kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90 % and 60 % of cases respectively. 20 % of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length hCG beta protein
    克隆位点
    HCGb-54
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CGB Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: JAR or TT cells. Placenta.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    CGB (Chorionic Gonadotropin, beta Polypeptide (CGB))
    别名
    CGB (CGB 产品)
    别名
    CGB antibody, CGB3 antibody, CGB5 antibody, CGB7 antibody, CGB8 antibody, hCGB antibody, CG-beta antibody, chorionic gonadotropin, beta polypeptide antibody, chorionic gonadotropin beta subunit 3 antibody, CGB antibody, CGB3 antibody
    背景
    CG-beta, CGB3, CGB5, CGB7, CGB8, Choriogonadotropin Subunit beta, hCGB,HCG-beta (Pregnancy & Choriocarcinoma Marker)
    Cellular localisation: Cytoplasmic, secreted
    分子量
    22kDa
    基因ID
    1082, 172944
    UniProt
    P01233
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