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P-Cadherin 抗体

This anti-P-Cadherin antibody is a 小鼠 单克隆 antibody detecting P-Cadherin in WB, IF 和 FACS. Suitable for 人.
产品编号 ABIN6936895
发货至: 中国

Quick Overview for P-Cadherin 抗体 (ABIN6936895)

抗原

See all P-Cadherin (CDH3) 抗体
P-Cadherin (CDH3)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This P-Cadherin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

12H6
  • 特异性

    Recognizes a protein of 116 kDa, identified as P-Cadherin-1 (CDH3). Itis a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congenital hypotrichosis with juvenile macular dystrophy.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant human P-cadherin fusion protein

    亚型

    IgG1 kappa
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL) Optimal dilution for a specific application should be determined.

    Positive_Control: A431 or PC-3 cells. Pancreas, Placenta or Prostate.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    P-Cadherin (CDH3)

    别名

    CDH3

    背景

    Cadherin 3 type 1, Cadherin-3, Cadp, Calcium dependent adhesion protein placental, CDH3, CDHP, HJMD, P-cadherin (Placental), PCAD, Placental cadherin,P-Cadherin (CDH3)
    Cellular localisation: Cell surface

    分子量

    116kDa

    基因ID

    1001, 191842

    UniProt

    P22223
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