LI Cadherin 抗体 (AA 242-418)
Quick Overview for LI Cadherin 抗体 (AA 242-418) (ABIN6936890)
抗原
See all LI Cadherin 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 242-418
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特异性
- It recognizes a protein of 120 kDa, which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment (around aa 242-418) of human Cadherin 17 protein (CDH17) (exact sequence is proprietary)
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亚型
- IgG2b kappa
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anti-LI Cadherin (AA 242-418) antibody
适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-517M unconjugated
anti-LI Cadherin antibody适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-LI Cadherin (AA 24-131) antibody适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1H3 unconjugated
anti-LI Cadherin antibody适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-LI Cadherin (AA 600-707) antibody适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 7D10E1 unconjugated
anti-LI Cadherin (AA 67-351) antibody适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-LI Cadherin (AA 242-418) antibody适用: 人 FACS, IHC (f) 宿主: 小鼠 Monoclonal CDH17-2618 unconjugated
anti-LI Cadherin (AA 101-200) antibody适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-LI Cadherin (Internal Region) antibody适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-LI Cadherin (AA 242-418) antibody适用: 人 WB, IHC (f) 宿主: 小鼠 Monoclonal CDH17-2617 unconjugated
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应用备注
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Known_Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HepG2 or HT29 cells. Stomach, Small Intestine, Colon or liver.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- LI Cadherin
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别名
- CDH17
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背景
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BILL-cadherin, Cadherin-17, CDH17, HPT-1 cadherin, human intestinal peptide-associated transporter HPT-1, human peptide transporter 1 (HPT-1), Intestinal peptide-associated transporter HPT-1, LI-cadherin (liver-intestine), Liver Cadherin, Liver-intestine cadherin,Cadherin 17 / LI Cadherin (Liver-Intestine Marker)
Cellular localisation: Cell Surface and Cytoplasmic -
分子量
- 120kDa
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基因ID
- 1015, 591853
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UniProt
- Q12864
抗原
-
