Cadherin-16 抗体 (AA 371-507)
Quick Overview for Cadherin-16 抗体 (AA 371-507) (ABIN6936887)
抗原
See all Cadherin-16 (CDH16) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 371-507
-
特异性
- This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
-
交叉反应 （详细）
- Human.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Recombinant fragment (around aa 371-507) of human CDH16 protein (exact sequence is proprietary)
-
亚型
- IgG2b kappa
-
-
anti-Cadherin-16 (CDH16) (AA 37-287) antibody
CDH16 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin-16 (CDH16) (AA 353-617) antibodyCDH16 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin-16 (CDH16) antibodyCDH16 适用: 人 WB, FACS, IHC (f) 宿主: 兔 Monoclonal CDH16-1532R unconjugated Recombinant Antibody
anti-Cadherin-16 (CDH16) (AA 19-230) antibodyCDH16 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cadherin-16 (CDH16) (AA 371-507) antibodyCDH16 适用: 人 WB, ELISA, IHC (f), Coat 宿主: 小鼠 Monoclonal CDH16-2125 unconjugated
anti-Cadherin-16 (CDH16) (AA 371-507) antibodyCDH16 适用: 人 ELISA, IHC (f), Coat 宿主: 小鼠 Monoclonal CDH16-2448 unconjugated
anti-Cadherin-16 (CDH16) antibodyCDH16 适用: 人 WB, FACS, IHC (f) 宿主: 小鼠 Monoclonal rCDH16-1071 unconjugated Recombinant Antibody
anti-Cadherin-16 (CDH16) (AA 1-829) antibodyCDH16 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Cadherin-16 (CDH16) antibodyCDH16 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-516R unconjugated Recombinant Antibody
anti-Cadherin-16 (CDH16) (C-Term) antibodyCDH16 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Known_Application: ELISA (For coating, order Ab without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Normal kidney or renal cell carcinoma.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- Cadherin-16 (CDH16)
-
别名
- CDH16
-
背景
-
Cadherin-16 (CDH16), Kidney-specific cadherin, Ksp-cadherin antibody,Ksp-Cadherin / CDH16 (Renal Cell Marker)
Cellular localisation: Cell Surface and Cytoplasmic -
分子量
- 130kDa
-
基因ID
- 1014, 513660
-
UniProt
- O75309
抗原
-
