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CD79a 抗体 (AA 202-216)

CD79A 适用: 人 FACS, IF, WB, IHC (f) 宿主: 小鼠 Monoclonal JCB117-HM47-A9 unconjugated
产品编号 ABIN6936812
发货至: 中国
  • 抗原 See all CD79a (CD79A) 抗体
    CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
    抗原表位
    • 68
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    AA 202-216
    适用
    • 183
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    宿主
    • 101
    • 96
    • 1
    小鼠
    克隆类型
    • 115
    • 82
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    单克隆
    标记
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    This CD79a antibody is un-conjugated
    应用范围
    • 112
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    Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.
    交叉反应 (详细)
    Human. Monkey. Pig. Cow. Mouse. Rat.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    A synthetic peptide corresponding to aa 202-216 (GTYQDVGSLNIADVQ) of human CD79a protein (JCB117 and HM47/A9).
    克隆位点
    JCB117-HM47-A9
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD79A Primary Antibody
  • 应用备注

    Known_Application: Western Blot (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Raji, Daudi or Ramos cells. Germinal center B- cells in a lymph node or tonsil.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
    别名
    CD79A (CD79A 产品)
    别名
    CD79A antibody, Ig-alpha antibody, Iga antibody, Igalpha antibody, Ly-54 antibody, Ly54 antibody, mb-1 antibody, IGA antibody, MB-1 antibody, IG-alpha antibody, CD79a molecule antibody, CD79A antigen (immunoglobulin-associated alpha) antibody, Cd79a molecule-like antibody, CD79A antibody, Cd79a antibody, Cd79al antibody
    背景
    B lymphocyte-specific MB1 protein, B-cell antigen receptor complex-associated protein alpha chain, CD79a molecule immunoglobulin associated alpha, Ig-alpha, IGA, IgM-alpha, Immunoglobulin-associated alpha, Ly54, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein,CD79a (B Cell Marker)
    Cellular localisation: Cell Surface
    分子量
    44kDa
    基因ID
    973, 631567
    UniProt
    P11912
    途径
    BCR Signaling
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