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CD2 抗体

This 小鼠 单克隆 antibody specifically detects CD2 in FACS, IF, WB 和 Func. It exhibits reactivity toward 人.
产品编号 ABIN6936629
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD2 抗体 (ABIN6936629)

抗原

See all CD2 抗体
CD2

适用

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小鼠

克隆类型

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单克隆

标记

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This CD2 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Functional Studies (Func)

克隆位点

1E7E8-G4
  • 原理

    CD2 / Lymphocyte Function Antigen 2 (LFA-2) Antibody

    特异性

    CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

    交叉反应 (详细)

    Human.

    纯化方法

    200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Human Thymocytes/Sezary T cells

    亚型

    IgG2a, kappa
  • 应用备注

    Known_Application: Functional Studies (Order Ab without Azide),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

    Positive_Control: MOLT-4, 293T or Jurkat cells. Lymph node and tonsil.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    CD2

    别名

    CD2

    背景

    Erythrocyte receptor, LFA-2, LFA-3 receptor, Ly-37, Lymphocyte function antigen 2, Rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5, T11

    293T or Jurkat cells. Lymph node and tonsil., Molt-4

    分子量

    ~50kDa

    基因ID

    914, 523500

    UniProt

    P06729
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