Recombinant CD1a 抗体
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- 抗原 See all CD1a 抗体
- CD1a
- 抗体类型
- Recombinant Antibody
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This CD1a antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human CD1a protein
- 克隆位点
- C1A-1506R
- 亚型
- IgG
- Top Product
- Discover our top product CD1a Primary Antibody
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anti-CD1a (CD1a) antibody
CD1a 适用: 人 IHC, WB, ELISA, ICC 宿主: 小鼠 Monoclonal 7A7 unconjugated
anti-CD1a (CD1a) (AA 151-250) antibodyCD1a 适用: 人 FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD1a (CD1a) antibodyCD1a 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rC1A-711 unconjugated Recombinant Antibody
anti-CD1a (CD1a) antibody (FITC)CD1a 适用: 人 FACS 宿主: 小鼠 Monoclonal HI149 FITC
anti-CD1a (CD1a) antibody (PE)CD1a 适用: 人 FACS 宿主: 小鼠 Monoclonal HI149 PE
anti-CD1a (CD1a) antibody (APC)CD1a 适用: 人 FACS 宿主: 小鼠 Monoclonal HI149 APC
anti-CD1a (CD1a) antibodyCD1a 适用: 人 IHC, StM 宿主: 兔 Monoclonal C1A-1506R unconjugated Recombinant Antibody
anti-CD1a (CD1a) antibodyCD1a 适用: 人, 猕猴 FACS, IF, IHC, WB, StM 宿主: 小鼠 Monoclonal O10 unconjugated
anti-CD1a (CD1a) (AA 1-311) antibodyCD1a 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal M1-2-1B5 unconjugated
anti-CD1a (CD1a) antibodyCD1a 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-001M unconjugated Recombinant Antibody
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: MOLT-4 cells. Paracortex in a tonsil or a reactive lymph node.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- CD1a
- 别名
- CD1A (CD1a 产品)
- 别名
- CD1 antibody, FCB6 antibody, HTA1 antibody, R4 antibody, T6 antibody, CD1A antibody, CD1a molecule antibody, CD1 antigen antibody, T-cell surface glycoprotein CD1a antibody, CD1A antibody, CD1.1 antibody, LOC100156095 antibody, LOC101111409 antibody
- 背景
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Cortical thymocyte antigen CD1A, Epidermal dendritic cell marker CD1a antibody, FCB6, HTA1, T cell surface antigen T6 / Leu 6, T-Cell Surface Glycoprotein CD1A,CD1a / HTA1 (Mature Langerhans Cells Marker)
Cellular localisation: Cell Surface and Cytoplasmic - 分子量
- 49kDa
- 基因ID
- 909, 1309
- UniProt
- P06126
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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