Caldesmon 抗体
Quick Overview for Caldesmon 抗体 (ABIN6936571)
抗原
See all Caldesmon (CALD1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120'150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70'80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
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无交叉反应
- 大鼠
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交叉反应 （详细）
- Human. Does not react with Rat.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human CALD1 protein
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亚型
- IgG1 kappa
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anti-Caldesmon 1 (CALD1) (AA 26-207) antibody
CALD1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6F8D2 unconjugated
anti-Caldesmon 1 (CALD1) (AA 434-531) antibodyCALD1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caldesmon 1 (CALD1) (pSer789) antibodyCALD1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caldesmon 1 (CALD1) antibodyCALD1 适用: 人, 大鼠 IHC, StM 宿主: 兔 Monoclonal CALD1-1424R unconjugated Recombinant Antibody
anti-Caldesmon 1 (CALD1) (C-Term) antibodyCALD1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caldesmon 1 (CALD1) (AA 1-240) antibodyCALD1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caldesmon 1 (CALD1) antibodyCALD1 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caldesmon 1 (CALD1) antibodyCALD1 适用: 人, 大鼠 IHC, StM 宿主: 兔 Polyclonal unconjugated
anti-Caldesmon 1 (CALD1) antibodyCALD1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CALD1-820 unconjugated
anti-Caldesmon 1 (CALD1) (AA 1-538) antibodyCALD1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Western Blot (2-4 μg/mL), Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 1 mM EDTA, pH 7.5-8.5, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: Uterus, Blood vessels in all tissues, smooth muscle or leiomyosarcoma.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
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别名
- CALD1
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背景
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CAD, CALD1, Caldesmon 1 Isoform 1, Caldesmon 1 Isoform 2, Caldesmon 1 Isoform 3, Caldesmon 1 Isoform 4, Caldesmon 1 Isoform 5, CDM, HCAD, LCAD, NAG22,Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker)
Cellular localisation: Cytoplasmic -
分子量
- 150kDa
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基因ID
- 800, 490203
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UniProt
- Q05682
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途径
- Myometrial Relaxation and Contraction
抗原
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