CA8 抗体
Quick Overview for CA8 抗体 (ABIN6936553)
抗原
See all CA8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in CA8 gene causes neuropathology, such as ataxia, mild mental retardation and the predisposition to quadrupedal gait. It is also associated with the development of colorectal and lung cancers. Additionally, it is upregulated in various cancers.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human CA8 protein
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亚型
- IgG2a kappa
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anti-Carbonic Anhydrase VIII (CA8) antibody
CA8 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CPTC-CA8-2 unconjugated
anti-Carbonic Anhydrase VIII (CA8) (AA 1-290) antibodyCA8 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Carbonic Anhydrase VIII (CA8) (AA 40-139) antibodyCA8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F7 unconjugated
anti-Carbonic Anhydrase VIII (CA8) (AA 40-139) antibodyCA8 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Carbonic Anhydrase VIII (CA8) (C-Term) antibodyCA8 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Carbonic Anhydrase VIII (CA8) (AA 31-80) antibodyCA8 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 豚鼠, 马, 猴, 兔, Bat, 小鸡, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Carbonic Anhydrase VIII (CA8) (C-Term) antibodyCA8 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 豚鼠, 马, 猴, 兔, Bat, 小鸡, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Carbonic Anhydrase VIII (CA8) (N-Term) antibodyCA8 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Carbonic Anhydrase VIII (CA8) (AA 1-290) antibodyCA8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human cerebellum. Selective expression in purkinje cells. HEK-293 or K-562 cell lines.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CA8 (Carbonic Anhydrase VIII (CA8))
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别名
- CA8
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背景
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CA-VIII, CALS, CARP, MGC120502, MGC99509,Carbonic Anhydrase VIII
Cellular localisation: Cytoplasm. Cell surface. -
分子量
- 32.97kDa
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基因ID
- 767, 654388
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UniProt
- P35219
抗原
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