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CD147 抗体

This anti-CD147 antibody is a 小鼠 单克隆 antibody detecting CD147 in FACS 和 IF. Suitable for 人.
产品编号 ABIN6936531
发货至: 中国

Quick Overview for CD147 抗体 (ABIN6936531)

抗原

See all CD147 (BSG) 抗体
CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD147 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

CB43
  • 特异性

    CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Native human leucocytes

    亚型

    IgM kappa
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: HSB2 cells. Renal Cell, Ovarian carcinoma or Melanoma.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Purified Ab WITHOUT BSA at 1.0mg/ml

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

    别名

    BSG

    背景

    5A11 Antigen, 5F7, Basigin, Blood brain barrier HT7 antigen BSG, Emmprin, Extracellular Matrix Metalloproteinase Inducer, Leukocyte Activation Antigen M6, Neurothelin, OK Blood Group Antigen, TCSF, Tumor Cell-derived Collagenase Stimulatory Factor,CD147 / EMMPRIN / Neurothelin
    Cellular localisation: Cell surface

    分子量

    35kDa (non-reduced), 40kDa (reduced)

    基因ID

    682, 501293

    UniProt

    P35613

    途径

    S100 Proteins
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