CD147 抗体
Quick Overview for CD147 抗体 (ABIN6936531)
抗原
See all CD147 (BSG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Native human leucocytes
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亚型
- IgM kappa
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: HSB2 cells. Renal Cell, Ovarian carcinoma or Melanoma.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Purified Ab WITHOUT BSA at 1.0mg/ml
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
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别名
- BSG
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背景
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5A11 Antigen, 5F7, Basigin, Blood brain barrier HT7 antigen BSG, Emmprin, Extracellular Matrix Metalloproteinase Inducer, Leukocyte Activation Antigen M6, Neurothelin, OK Blood Group Antigen, TCSF, Tumor Cell-derived Collagenase Stimulatory Factor,CD147 / EMMPRIN / Neurothelin
Cellular localisation: Cell surface -
分子量
- 35kDa (non-reduced), 40kDa (reduced)
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基因ID
- 682, 501293
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UniProt
- P35613
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途径
- S100 Proteins
抗原
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