BCL10 抗体 (AA 122-168)
Quick Overview for BCL10 抗体 (AA 122-168) (ABIN6936469)
抗原
See all BCL10 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 122-168
-
特异性
- BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1,14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF14) translocation, while 55 % of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
-
交叉反应 (详细)
- Human.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Human BCL10 recombinant protein (epitope aa122-168)
-
亚型
- IgG1 kappa
-
-
-
-
应用备注
-
Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: WEHI-231 or Ramos cells. Lymphoma.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
-
别名
- BCL10
-
背景
-
B-cell CLL/lymphoma 10, B-cell leukemia/lymphoma 10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, caspase-recruiting domain-containing protein, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular homolog of vCARMEN, Cellular-E10 (cE10), CIPER, hCLAP, mE10, R-RCD1,BCL10 (MALT-Lymphoma Marker)
Cellular localisation: Nuclear and cytoplasmic -
分子量
- 33kDa
-
基因ID
- 8915, 193516
-
UniProt
- O95999
-
途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
抗原
-