APCS 抗体 (AA 143-223)
Quick Overview for APCS 抗体 (AA 143-223) (ABIN6936424)
抗原
See all APCS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 143-223
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特异性
- Serum amyloid P (SAP) is a glycoprotein belonging to the pentraxin family of proteins, which has a characteristic pentameric organization and calciumdependent ligand binding. Secreted by liver epithelial cells, SAP is found in serum and urine. Although the function of SAP has not been clearly established, it has been shown to interact with DNA and histones and is thought to play a role in scavenging nuclear material released from damaged circulating cells. Also designated PTX2, SAP is a precursor of the protein amyloid P component (AP), which is universally associated with the amyloid deposits in all forms of amyloidoses, including Alzheimer s disease. SAP is a decamer of ten identical, noncovalently linked subunits, each of which may be post-translationally modified by glycosylation.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment of human APCS protein (around aa 143-223) (exact sequence is proprietary)
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亚型
- IgG2b kappa
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anti-Amyloid P Component, Serum (APCS) (AA 23-223) antibody
APCS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid P Component, Serum (APCS) (AA 22-222) antibodyAPCS 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid P Component, Serum (APCS) (AA 1-223) antibodyAPCS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid P Component, Serum (APCS) (AA 143-223) antibodyAPCS 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal APCS-3240 unconjugated
anti-Amyloid P Component, Serum (APCS) (AA 35-149) antibodyAPCS 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F3 unconjugated
anti-Amyloid P Component, Serum (APCS) (AA 117-223) antibodyAPCS 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Amyloid P Component, Serum (APCS) antibodyAPCS 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid P Component, Serum (APCS) antibodyAPCS 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 5A9 unconjugated
anti-Amyloid P Component, Serum (APCS) (AA 117-223) antibodyAPCS 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E8 unconjugated
anti-Amyloid P Component, Serum (APCS) (Internal Region) antibodyAPCS 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Human endometrial carcinoma tissue (IHC).
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- APCS (Amyloid P Component, Serum (APCS))
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别名
- APCS
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背景
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9.5S alpha 1 glycoprotein, Amyloid P component serum (APCS), Pentaxin related, Pentraxin 2 (PTX2), Serum Amyloid P (SAP), Serum amyloid P component,Serum Amyloid P / APCS
Cellular localisation: Secreted. -
分子量
- 200kDa (oligomeric), 26kDa (non-covalently bound subunit), 30kDa (glycosylated SAP subunit)
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基因ID
- 325, 507080
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UniProt
- P02743
抗原
-
