Annexin a1 抗体
Quick Overview for Annexin a1 抗体 (ABIN6936422)
抗原
See all Annexin a1 (ANXA1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human Annexin A1 protein
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亚型
- IgG2a kappa
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anti-Annexin A1 (ANXA1) (AA 6-346) antibody
ANXA1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) (AA 1-346) antibodyANXA1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) antibodyANXA1 适用: 人 IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal ANXA1-3566 unconjugated
anti-Annexin A1 (ANXA1) (AA 144-248) antibodyANXA1 适用: 人, 小鼠, 猴 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Annexin A1 (ANXA1) antibodyANXA1 适用: 人 WB, IP, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) (C-Term) antibodyVerified ANXA1 适用: 人, 小鼠, 大鼠, Pig WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) (AA 1-346) antibodyANXA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-Annexin A1 (ANXA1) (AA 1-346) antibodyANXA1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) antibodyANXA1 适用: 人 IHC, FACS, StM 宿主: 小鼠 Monoclonal ANXA1-1671 unconjugated
anti-Annexin A1 (ANXA1) antibodyANXA1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, A549, A431 and K562 cell lysates, human esophagus, placenta and prostate tissues.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
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别名
- ANXA1
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背景
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ANXA1, ANX1, Annexin-1, Chromobindin-9, LPC1, p35,Annexin A1 / (Hairy Cell Leukemia Marker)
Cellular localisation: Nuclear, Cytoplasm and Cell Surface -
分子量
- 38kDa
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基因ID
- 301, 494173
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UniProt
- P04083
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途径
- Hormone Transport
抗原
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