CD13 抗体
Quick Overview for CD13 抗体 (ABIN6936413)
抗原
See all CD13 (ANPEP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes an integral membrane glycoprotein of 150 kDa, identified as CD13 (also known as aminopeptidase-N). The CD13 antigen is present on most cells of myeloid origin including granulocytes, monocytes, mast cells, and GM-progenitor cells. It is also expressed by the majority of AML, CML in myeloid blast crisis, and in a smaller fraction of lymphoid leukemias. CD13 is absent from normal lymphocytes, platelets and erythrocytes. CD13 is also present on fibroblasts, endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteoclasts, and cells lining bile duct canaliculi. CD13 is identical to aminopeptidase N (APN), a prominent membrane-bound metalloprotease present on the surface of intestinal brush border and renal tubules. CD13 plays a role in metabolism of biologically active peptides, in phagocytosis, and in bactericidal/tumoricidal activities. It also serves as a receptor for human coronaviruses (HCV). The lineage-restricted pattern of expression of CD13 within the hemopoietic compartment suggests that it may be important in myeloid cell differentiation.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- KG-1 myeloid cells
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亚型
- IgG1 kappa
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anti-Alanyl (Membrane) Aminopeptidase (ANPEP) (AA 668-967) antibody
ANPEP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Alanyl (Membrane) Aminopeptidase (ANPEP) (AA 344-444) antibodyANPEP 适用: 人, 小鼠 FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Alanyl (Membrane) Aminopeptidase (ANPEP) (AA 34-219) antibodyANPEP 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Alanyl (Membrane) Aminopeptidase (ANPEP) antibodyANPEP 适用: 人, Non-Human Primate FACS, IHC (fro), IP 宿主: 小鼠 Monoclonal WM15 unconjugated
anti-Alanyl (Membrane) Aminopeptidase (ANPEP) antibodyANPEP 适用: 人, Non-Human Primate FACS, IHC (fro), IP, Func 宿主: 小鼠 Monoclonal WM15 unconjugated
anti-Alanyl (Membrane) Aminopeptidase (ANPEP) (AA 781-967) antibodyANPEP 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 1C7D7 unconjugated
anti-Alanyl (Membrane) Aminopeptidase (ANPEP) antibody (Biotin)ANPEP 适用: 人, Non-Human Primate FACS, IHC (fro), IP 宿主: 小鼠 Monoclonal WM15 Biotin
anti-Alanyl (Membrane) Aminopeptidase (ANPEP) antibody (FITC)ANPEP 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal WM15 FITC
anti-Alanyl (Membrane) Aminopeptidase (ANPEP) antibody (PE)ANPEP 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal WM15 PE
anti-Alanyl (Membrane) Aminopeptidase (ANPEP) antibody (PerCP)ANPEP 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal WM15 PerCP
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Frozen) (1-2 μg/mL for 30 min at RT)Optimal dilution for a specific application should be determined.
Positive_Control: Macrophages in a lymph node/tonsil or in any normal tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
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别名
- ANPEP
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背景
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Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N, ANPEP, AP-M, APN, gp150, hAPN, Lap1, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, p150, PEPN,CD13 / Aminopeptidase-N (Myeloid Cell Marker)
Cellular localisation: Cell Surface -
分子量
- 150kDa
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基因ID
- 290, 1239
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UniProt
- P15144
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途径
- Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
-
