AMPD3 抗体
Quick Overview for AMPD3 抗体 (ABIN6936408)
抗原
See all AMPD3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- It recognizes a protein of ~90 kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human AMDP3 protein
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亚型
- IgG2b kappa
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anti-Adenosine Monophosphate Deaminase 3 (AMPD3) antibody
AMPD3 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal AMPD3-901 unconjugated
anti-Adenosine Monophosphate Deaminase 3 (AMPD3) (AA 1-260) antibodyAMPD3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Monophosphate Deaminase 3 (AMPD3) (AA 325-356) antibodyAMPD3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB17671 unconjugated
anti-Adenosine Monophosphate Deaminase 3 (AMPD3) antibodyAMPD3 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Monophosphate Deaminase 3 (AMPD3) antibodyAMPD3 适用: 人 IF, ICC, FACS, IHC (p) 宿主: 小鼠 Monoclonal AMPD3-901 unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: RBC. Fetal liver, Spleen or Placenta.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))
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别名
- AMPD3
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背景
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Adenosine monophosphate deaminase (isoform E), AMP aminohydrolase, AMP deaminase 3, AMP deaminase isoform E, Ampd3, Erythrocyte AMP deaminase, Erythrocyte specific AMP deaminase, Erythrocyte specific protein, Erythrocyte type AMP deaminase, Myoadenylate deaminase,AMP Deaminase, Isoform E (AMPD3) (Erythroid Marker)
Cellular localisation: Cell Surface -
分子量
- ~90kDa
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基因ID
- 272, 501890
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UniProt
- Q01432
抗原
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