ALPL 抗体
Quick Overview for ALPL 抗体 (ABIN6936394)
抗原
See all ALPL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
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交叉反应 （详细）
- Human. Cow.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Bovine intestinal alkaline phosphatase
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亚型
- IgG1 kappa
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anti-Alkaline Phosphatase, Liver/bone/kidney (ALPL) (AA 18-335) antibody
ALPL 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Alkaline Phosphatase, Liver/bone/kidney (ALPL) antibodyALPL 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-Alkaline Phosphatase, Liver/bone/kidney (ALPL) antibodyALPL 适用: 人, Cow IHC, StM 宿主: 小鼠 Monoclonal ALPL-597 unconjugated
anti-Alkaline Phosphatase, Liver/bone/kidney (ALPL) (AA 21-35), (N-Term) antibodyALPL 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Alkaline Phosphatase, Liver/bone/kidney (ALPL) (AA 217-246) antibodyALPL 适用: 人, 小鼠 WB, ELISA, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Alkaline Phosphatase, Liver/bone/kidney (ALPL) (AA 91-200) antibodyALPL 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 4H1 unconjugated
anti-Alkaline Phosphatase, Liver/bone/kidney (ALPL) (Internal Region) antibodyALPL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Alkaline Phosphatase, Liver/bone/kidney (ALPL) (AA 20-270) antibodyALPL 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Alkaline Phosphatase, Liver/bone/kidney (ALPL) antibodyALPL 适用: 人 WB, IHC (p), FACS, EIA 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-Alkaline Phosphatase, Liver/bone/kidney (ALPL) (AA 52-150) antibodyALPL 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Frozen) (1-2 μg/mL for 30 minutes at RT)Optimal dilution for a specific application should be determined.
Positive_Control: Intestine.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))
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别名
- ALPL
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背景
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Alkaline phosphatase, germ cell, Alkaline phosphatase, testicular and thymus, Alkaline phosphatase liver/bone/kidney, Alkaline phosphatase, tissue-nonspecific, ALPG, ALPL, Germ cell alkaline phosphatase, Testicular and thymus alkaline phosphatase, Tissue non-specific alkaline phosphatase, Tissue nonspecific ALP (TNAP or TNSALP),Alkaline Phosphatase (Tissue-Nonspecific)
Cellular localisation: Cell Surface -
分子量
- 55kDa
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基因ID
- 249, 75431
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UniProt
- P05186
抗原
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